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Yankton staff nurses can make a mean salary of about $46,000 per year. Employers of RNs include the Avera Sacred Heart Hospital, which is within the city limits. Yankton is a city in South Dakota, in Yankton County, and is a bedroom community for Sioux Falls, which is located to the northeast. Public transportation is not available in the area. A car, if available, is generally the sole means for commuting to Sioux Falls. The city was founded in 1859, as a result of the presence of a treaty permitting settlement. Nurses seeking to further their educations will find courses at Mount Marty College. Submit your resume to be matched to jobs in Yankton.