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The six hundred sixty-first largest city in the United States, Owensboro, Kentucky is home to a population of just over 54,000 people. Located in the Tri-State region of Illinois, Kentucky, and Indiana; Owensboro's economy revolves heavily around construction, metal products, hospitality, utilities, education, and health care. The city is served by a number of large medical facilities, including Owensboro Mercy Health Center, River Valley Behavioral Health, and the Methodist Hospital. Submit your resume to be matched to jobs in Owensboro.